AGILENT 6560 IM-QTOF Mass Spectrometer


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  • Brand: AGILENT
  • Type: Mass Spectrometer
  • Model: 6560 IM-QTOF
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AGILENT 6560 IM-QTOF Mass Spectrometer

AGILENT 6560 IM-QTOF Mass Spectrometer, The NEW Agilent 6560C ion mobility Q-TOF LC/MS system delivers unrivaled separation and selectivity by combining chromatography, ion mobility, and mass spectrometry. The 6560C Q-TOF LC/MS can even uncover structural information that cannot be seen with traditional LC/MS systems, including separation of in-class isomers via high-resolution demultiplexing (HRdm).

The system features innovative electrodynamic ion funnel technology to dramatically improve sensitivity while maintaining an attractive low field drift tube design. This allows you to directly measure accurate collision cross sections (CCS) and preserve labile targets. Whether you are looking to create a more comprehensive profile of metabolomics samples, characterize complex polymeric mixtures, or understand structural changes in biomolecules, ion mobility mass spectrometry provides access to new information

  • First-principle based collision cross-section measurement and accuracy without standards.
  • Utmost separation capacity, combining UHPLC, ion mobility, and high resolution mass spectrometry.
  • Better separation of complex isobaric classes such as lipids and glycans.
  • In-depth characterization of structural conformations and isomeric compounds.
  • Conservation of structural fidelity of molecules in the gas phase using the low-energy drift tube design.
  • Multiplexing for substantially increased sensitivity and dynamic range, with enhancement of one order of magnitude.
  • Ion mobility resolution of up to 200 in full spectra can be achieved via postprocessing with the Agilent high resolution demultiplexing ( HRdm 2.0) software.
  • Collision-induced unfolding (CIU) for quantitative structural analysis of proteins includes in-source activation for induced fragmentation of molecules.
  • Up to 5 Hz acquisition rate can be used without compromising resolution for UHPLC compatibility.
  • Utilizes Agilent VacShield for vent-free capillary removal.
In-spectra Dynamic Range
  • 5 Orders
Ion Mobility Resolution (FWHM)
  • >200
Ion Source
  • Dual-AJS
  • Dual-ESI
  • APCI
  • MultiMode (ESI+APCI)
  • NanoESI
MS Acquisition Rate
  • 50 spectra/second
MS Mass Accuracy (positive)
  • <1 ppm RMS
MS Sensitivity (positive)
  • S/N (RMS) > 50:1. Measured with 1pg reserpine on column
MS/MS Acquisition Rate
  • 30 spectra/second
MS/MS Mass Accuracy (positive)
  • <2 ppm RMS
Quad Resolution (FWHM)
  • 1.3 Da (autotune)
Quadrupole Isolation Mass Range
  • m/z 20-4000
Software Platform
  • MassHunter
Supported Software Add-Ons
  • MassHunter BioConfirm
  • MassHunter VistaFlux
  • Mass Profiler Professional
  • Classifier
  • Lipid Annotator
TOF Mass Range
  • m/z 20-20,000
TOF Mass Resolution (FWHM)
  • > 42,000 at m/z 2,722 independent of acquisition rate
Temperature Mass Stability
  • <1 ppm / 3 °C
Ventless Maintenance
  • VacShield Technology

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